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Madrigal Pharmaceuticals
Madrigal Pharmaceuticals
(MDGL)
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Clinical Trials
Therapeutic Areas:
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Classification:
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Approval:
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Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Resmetirom
healthy volunteers/patients
,
hepatic insufficiency
,
renal insufficiency
,
hyperlipoproteinemia type ii
,
alcoholic fatty liver
,
acquired immunodeficiency syndrome
,
hiv-2
,
non-alcoholic fatty liver disease
,
fibrosis
,
liver diseases
,
liver cirrhosis
,
fatty liver
,
hyperlipidemias
,
dyslipidemias
,
thyroid hormone resistance syndrome
Aglatimagene besadenovec
breast neoplasms
,
ovarian neoplasms
,
renal cell carcinoma
,
colorectal neoplasms
,
pancreatic neoplasms
,
melanoma
,
liver neoplasms
,
squamous cell neoplasms
,
mesothelioma
,
follicular lymphoma
,
small cell lung carcinoma
,
triple negative breast neoplasms
,
neoplasms
,
adenocarcinoma
,
squamous cell carcinoma of head and neck
,
prostatectomy
,
castration-resistant prostatic neoplasms
,
recurrence
,
prostatic neoplasms
,
prostatic hyperplasia
,
urinary bladder neck obstruction
,
disease progression
,
neoplasm metastasis
,
erectile dysfunction
,
hypertension
,
diabetes mellitus
,
motor activity
,
coronary artery disease
,
hypersensitivity
Ganetespib
carcinoma
,
multiple myeloma
,
transitional cell carcinoma
,
male breast neoplasms
,
esophageal neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia chronic-phase
,
blast crisis
,
lymphoid leukemia
,
myeloproliferative disorders
,
neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
rectal neoplasms
,
prostatic neoplasms
,
sarcoma
,
ovarian epithelial carcinoma
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
small cell lung carcinoma
,
melanoma
,
hemangiosarcoma
,
pathologic complete response
,
gastrointestinal stromal tumors
,
ovarian neoplasms
,
malignant mesothelioma
,
mesothelioma
,
disorders of sex development
,
recurrence
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
colonic neoplasms
,
pancreatic neoplasms
,
uveal neoplasms
,
lung neoplasms
,
non-small-cell lung carcinoma
Calcium dobesilate
macular degeneration
,
retinal neovascularization
,
vitrectomy
,
radiation injuries
,
uveal neoplasms
,
uveal melanoma
,
capsule opacification
,
papilledema
,
macular edema
,
retinal vein occlusion
,
diabetic retinopathy
,
diabetes mellitus
,
epiretinal membrane
,
edema
,
cataract
,
posterior uveitis
,
uveitis
,
ischemia
,
retinal diseases
,
intermediate uveitis
,
pars planitis
,
dental deposits
,
visual acuity
APILIMOD
leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
inflammation
,
immunologic deficiency syndromes
,
common variable immunodeficiency
,
crohn disease
,
covid-19
,
rheumatoid arthritis
,
arthritis
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
dementia
,
frontotemporal dementia
,
primary progressive aphasia
,
pick disease of the brain
Bevifimod
healthy volunteers/patients
,
uveal neoplasms
,
cutaneous malignant melanoma
,
uveal melanoma
,
huntington disease
,
uveitis
,
urologic neoplasms
,
plasma cell neoplasms
,
chronic hepatitis c
,
mantle-cell lymphoma
,
biliary tract neoplasms
,
esophageal neoplasms
,
transitional cell carcinoma
,
choroidal neovascularization
,
sarcoma
,
acquired immunodeficiency syndrome
,
fibrosis
,
graft vs host disease
,
central nervous system neoplasms
,
unknown primary neoplasms
,
genomic instability
,
lobular carcinoma
,
invasive hydatidiform mole
,
ischemia
,
coronary artery disease
,
myocardial ischemia
,
stroke
,
subarachnoid hemorrhage
,
aneurysm
,
aids-related complex
,
arthritis
,
esophageal squamous cell carcinoma
,
idiopathic pulmonary fibrosis
,
cholangiocarcinoma
,
emphysema
,
pulmonary emphysema
,
margins of excision
,
waldenstrom macroglobulinemia
,
aids-related lymphoma
,
hemolytic-uremic syndrome
,
thrombotic thrombocytopenic purpura
,
syndrome
,
thrombocytopenic purpura
,
purpura
,
azotemia
,
hereditary sensory and autonomic neuropathies
,
b-cell lymphoma marginal zone
,
uterine neoplasms
,
female genital neoplasms
,
sjogren's syndrome
,
nervous system neoplasms
,
burkitt lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
sex cord-gonadal stromal tumors
,
erythema multiforme
,
immunoblastic lymphadenopathy
,
obesity
,
overweight
,
lymphoma
,
large b-cell lymphoma diffuse
,
liver neoplasms
,
b-cell lymphoma
,
hepatocellular carcinoma
,
triple negative breast neoplasms
,
renal cell carcinoma
,
follicular lymphoma
,
rectal neoplasms
,
neoplasm metastasis
,
macular degeneration
,
glioblastoma
,
melanoma
,
adenocarcinoma
,
macular edema
,
multiple myeloma
,
carcinoma
,
pancreatic neoplasms
,
recurrence
,
hematologic neoplasms
,
inflammatory breast neoplasms
,
glioma
,
neoplasms by histologic type
,
neoplasms by site
,
brain neoplasms
,
colonic neoplasms
,
uterine cervical neoplasms
,
type 2 diabetes mellitus
,
ulcerative colitis
,
head and neck neoplasms
,
hemophilia a
,
thrombocytopenic purpura idiopathic
,
relapsing-remitting multiple sclerosis
,
nasal polyps
,
lung neoplasms
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
urinary bladder neoplasms
,
lymphoproliferative disorders
,
ovarian epithelial carcinoma
,
malignant mesothelioma
,
diabetic retinopathy
,
bronchiolitis obliterans syndrome
,
neuroblastoma
,
hemolysis
,
circulating neoplastic cells
,
retinal diseases
,
vision disorders
,
eye diseases
,
bcr-abl positive chronic myelogenous leukemia
,
pemphigus
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
nerve tissue neoplasms
,
myeloid leukemia acute
,
guillain-barre syndrome
,
patient preference
,
large-cell lymphoma anaplastic
,
anaplastic thyroid carcinoma
,
papillary thyroid cancer
,
laryngeal neoplasms
,
erdheim-chester disease
,
prostatic neoplasms
,
salivary gland neoplasms
,
skin neoplasms
,
gallbladder neoplasms
,
diabetes mellitus
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
membranous glomerulonephritis
,
colitis
,
disability evaluation
,
cognition disorders
,
hemolytic anemia autoimmune
,
nephrotic syndrome
,
focal segmental glomerulosclerosis
,
lipoid nephrosis
,
graft rejection
,
retinal neovascularization
,
type 3 von willebrand disease
,
breast neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
neoplasms
,
rheumatoid arthritis
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
anemia
,
hiv infections
,
ovarian neoplasms
,
stomach neoplasms
,
leukemia
,
lymphoid leukemia
,
kidney transplantation
,
chronic hepatitis b
,
heart transplantation
,
chronic kidney failure
,
fallopian tube neoplasms
,
liver transplantation
,
kidney diseases
,
chronic renal insufficiency
,
granulomatosis with polyangiitis
,
peritoneal neoplasms
,
pulmonary fibrosis
,
microscopic polyangiitis
,
renal insufficiency
,
asthma
,
transplantation
,
immunosuppression therapy
,
covid-19
,
polyomavirus infections
,
thrombosis
,
food hypersensitivity
,
liver cirrhosis
,
adenocarcinoma of lung
,
hepatitis b
,
hepatitis
,
hepatitis a
,
off-label use
,
retinal vein occlusion
,
cardiotoxicity
,
acute kidney injury
,
hemorrhage
,
endometrial neoplasms
,
uterine hemorrhage
,
postmenopause
,
hematopoietic stem cell transplantation
,
hiv-1
,
spinal muscular atrophy
,
spinal muscular atrophies of childhood
,
alzheimer disease
,
frontotemporal dementia
,
progressive supranuclear palsy
,
pick disease of the brain
,
hodgkin disease
Edodekin alfa
non-hodgkin lymphoma
,
asthma
,
pulmonary eosinophilia
Elesclomol
prostatic neoplasms
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
non-small-cell lung carcinoma
,
sarcoma
,
neoplasm metastasis
,
neoplasms
,
melanoma
Nepidermin
rectal neoplasms
,
endometrial neoplasms
,
squamous cell carcinoma
,
squamous cell neoplasms
,
salivary gland neoplasms
,
endometrioid carcinoma
,
breast neoplasms
,
prostatic neoplasms
,
colorectal neoplasms
,
lung neoplasms
,
non-small-cell lung carcinoma
,
head and neck neoplasms
,
multiple myeloma
,
neoplasms
,
hypercholesterolemia
,
liver neoplasms
,
stomach neoplasms
,
neoplasm metastasis
,
pancreatic neoplasms
,
osteoporosis
,
hepatocellular carcinoma
,
local neoplasm recurrence
,
huntington disease
,
multiple sclerosis
,
sclerosis
,
b-cell chronic lymphocytic leukemia
,
hyperlipoproteinemia type ii
,
myeloid leukemia acute
,
asthma
,
liver diseases
,
digestive system diseases
,
thyroid neoplasms
,
thyroid diseases
,
carcinoma
,
tonsillitis
,
lymphoproliferative disorders
,
paraproteinemias
,
immunoproliferative disorders
,
recurrence
,
adenocarcinoma
,
plasma cell neoplasms
,
drug therapy
,
heart failure
,
postmenopausal osteoporosis
,
pneumonia
,
gaucher disease
ROSABULIN
neoplasms
,
leukemia
,
hematologic neoplasms
,
lymphoma
Globulin, immune
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
non-small-cell lung carcinoma
,
knee osteoarthritis
,
carcinoma
,
hidradenitis suppurativa
,
sarcoidosis
,
abscess
,
fistula
,
asthma
,
melanoma
,
renal cell carcinoma
,
neoplasm metastasis
,
skin diseases
,
respiratory syncytial virus infections
,
psoriatic arthritis
,
juvenile arthritis
,
infections
,
ulcerative colitis
,
hiv infections
,
uveitis
,
osteoarthritis
,
congenital heart defects
,
premature birth
,
bronchopulmonary dysplasia
,
inflammatory bowel diseases
,
hiv
,
inflammation
,
mucositis
,
giant cell arteritis
,
behcet syndrome
,
interstitial cystitis
,
rheumatoid arthritis
,
psoriasis
,
crohn disease
,
arthritis
,
ankylosing spondylitis
,
spondylarthritis
,
acquired immunodeficiency syndrome
,
coronary artery disease
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
cardiovascular diseases
,
joint diseases
,
enterocolitis
,
hepatitis c
,
hepatitis b
,
hiv-2
,
hepatitis b virus
,
respiratory tract infections
,
communicable diseases
,
virus diseases
,
respiratory syncytial viruses
,
pain
,
fatigue
Biib-028
breast neoplasms
,
male breast neoplasms
,
melanoma
Anthracycline
sarcoma
,
hepatocellular carcinoma
,
liver neoplasms
,
rhabdomyosarcoma
,
carcinoma
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
breast neoplasms
Aminoglycoside
neoplasms
,
hepatocellular carcinoma
,
liver neoplasms
,
sarcoma
,
rhabdomyosarcoma
,
pneumonia
,
carcinoma
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
breast neoplasms
Doxorubin
non-hodgkin lymphoma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
invasive hydatidiform mole
,
follicular lymphoma
,
endometrial neoplasms
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