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Company ReportsMadrigal Pharmaceuticals

Madrigal Pharmaceuticals(MDGL)

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Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

alcoholic fatty liver

,

non-alcoholic fatty liver disease

,

,

,

liver cirrhosis

,

Aglatimagene besadenovec

prostatic neoplasms

Calcium dobesilate

healthy volunteers/patients

,

,

,

cesarean section

,

castration-resistant prostatic neoplasms

,

endometrioid carcinoma

,

hairy cell leukemia

,

sickle cell anemia

,

,

sleep deprivation

,

pituitary neoplasms

,

,

pituitary diseases

,

,

oligodendroglioma

,

prediabetic state

,

malignant mesothelioma

,

,

beta-thalassemia

,

,

hemoglobinopathies

,

aortic coarctation

,

systemic mastocytosis

,

,

central serous chorioretinopathy

,

,

,

,

autonomic nervous system diseases

,

,

esophageal diseases

,

,

lacrimal apparatus diseases

,

,

neuroepithelial neoplasms

,

medulloblastoma

,

,

,

,

spinal cord neoplasms

,

large granular lymphocytic leukemia

,

choroid plexus neoplasms

,

craniopharyngioma

,

primitive neuroectodermal tumors

,

choriocarcinoma

,

,

,

endodermal sinus tumor

,

neuroectodermal tumors

,

,

phenylketonurias

,

chromophobe adenoma

,

basophil adenoma

,

acidophil adenoma

,

,

,

multiple pulmonary nodules

,

solitary pulmonary nodule

,

emergence delirium

,

,

alcohol drinking

,

retinal telangiectasis

,

retinal perforations

,

insulin resistance

,

non-alcoholic fatty liver disease

,

,

,

,

tooth extraction

,

bone transplantation

,

,

,

hematologic neoplasms

,

follicular lymphoma

,

t-cell leukemia

,

b-cell lymphoma marginal zone

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

plasma cell leukemia

,

squamous cell carcinoma

,

b-cell chronic lymphocytic leukemia

,

large-cell lymphoma anaplastic

,

adult t-cell leukemia-lymphoma

,

,

,

squamous cell carcinoma of head and neck

,

germ cell and embryonal neoplasms

,

,

,

t-cell lymphoma cutaneous

,

intraocular lymphoma

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

lymphomatoid granulomatosis

,

nasopharyngeal carcinoma

,

,

radiation injuries

,

uveal neoplasms

,

,

pancreatic neoplasms

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

hemophagocytic lymphohistiocytosis

,

oral lichen planus

,

,

squamous cell neoplasms

,

cholangiocarcinoma

,

,

esophageal neoplasms

,

,

sudden hearing loss

,

myeloid leukemia chronic-phase

,

vitreous hemorrhage

,

pathologic complete response

,

,

extranodal nk-t-cell lymphoma

,

sezary syndrome

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

,

nervous system neoplasms

,

laryngeal neoplasms

,

laryngeal diseases

,

b-cell leukemia

,

,

wet macular degeneration

,

,

endocrine gland neoplasms

,

,

pelvic organ prolapse

,

,

clonal hematopoiesis

,

,

colonic neoplasms

,

rectal neoplasms

,

,

cerebral toxoplasmosis

,

bone marrow transplantation

,

homologous transplantation

,

autologous transplantation

,

bullous pemphigoid

,

benign mucous membrane pemphigoid

,

bronchiolitis obliterans syndrome

,

biliary tract neoplasms

,

ductal carcinoma

,

blastic plasmacytoid dendritic cell neoplasm

,

,

,

nasopharyngeal neoplasms

,

epstein-barr virus infections

,

fuchs' endothelial dystrophy

,

hereditary corneal dystrophies

,

retinitis pigmentosa

,

,

,

hematologic diseases

,

myeloid leukemia accelerated phase

,

,

choroidal neovascularization

,

retinal neovascularization

,

pathologic neovascularization

,

,

gouty arthritis

,

testicular neoplasms

,

airway obstruction

,

,

,

,

congenital abnormalities

,

small cell carcinoma

,

,

,

,

esophageal squamous cell carcinoma

,

interstitial lung diseases

,

respiratory signs and symptoms

,

intratympanic injection

,

,

parkinsonian disorders

,

,

carbon monoxide poisoning

,

,

,

,

immunoglobulin light-chain amyloidosis

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

,

myeloid leukemia

,

smoldering multiple myeloma

,

philadelphia chromosome

,

hodgkin disease

,

hypersensitivity

,

brain neoplasms

,

myelodysplastic syndromes

,

,

myeloid leukemia acute

,

,

,

,

ovarian neoplasms

,

central nervous system neoplasms

,

biphenotypic leukemia acute

,

neoplasm metastasis

,

,

,

,

ataxia telangiectasia

,

,

,

,

ovarian epithelial carcinoma

,

,

oropharyngeal neoplasms

,

coronavirus infections

,

severe acute respiratory syndrome

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

,

adrenocortical hyperfunction

,

,

inborn genetic diseases

,

bronchopulmonary dysplasia

,

,

,

laparoscopic cholecystectomy

,

fallopian tube neoplasms

,

,

rotator cuff injuries

,

human influenza

,

viral pneumonia

,

cerebellar ataxia

,

small cell lung carcinoma

,

,

,

nervous system diseases

,

,

congenital adrenal hyperplasia

,

adrenogenital syndrome

,

,

,

thrombocytopenic purpura

,

,

liver neoplasms

,

,

,

,

,

,

,

ovarian hyperstimulation syndrome

,

uterine hemorrhage

,

promyelocytic leukemia acute

,

respiratory tract infections

,

,

communicable diseases

,

kidney diseases

,

,

traumatic brain injuries

,

,

unknown primary neoplasms

,

,

substance-related disorders

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

,

hyperbilirubinemia

,

,

conduction anesthesia

,

forearm injuries

,

,

replacement arthroplasty hip

,

male genital neoplasms

,

,

,

,

ocular motility disorders

,

,

opsoclonus-myoclonus syndrome

,

,

,

bone marrow diseases

,

viral conjunctivitis

,

acquired immunodeficiency syndrome

,

immune reconstitution inflammatory syndrome

,

atopic dermatitis

,

allergic rhinitis

,

allergic rhinitis perennial

,

,

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

refractory anemia with excess of blasts

,

erythroblastic leukemia acute

,

refractory anemia

,

digestive system surgical procedures

,

breast carcinoma in situ

,

,

,

,

hepatocellular carcinoma

,

spinal dysraphism

,

acanthamoeba keratitis

,

,

agranulocytosis

,

feeding behavior

,

multiple myeloma

,

plasma cell neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

lymphoid leukemia

,

,

,

,

,

postoperative pain

,

,

postoperative nausea and vomiting

,

non-hodgkin lymphoma

,

,

,

retinal vein occlusion

,

,

b-cell lymphoma

,

,

,

,

retinal diseases

,

breast neoplasms

,

large b-cell lymphoma diffuse

,

diabetic retinopathy

,

dry eye syndromes

,

,

replacement arthroplasty knee

,

,

prostatic neoplasms

,

thrombocytopenic purpura idiopathic

,

diabetes mellitus

,

t-cell lymphoma

,

thrombocytopenia

,

non-small-cell lung carcinoma

,

keratoconjunctivitis sicca

,

respiratory distress syndrome

,

,

t-cell lymphoma peripheral

,

epiretinal membrane

,

,

burkitt lymphoma

,

,

local anesthesia

,

,

,

newborn respiratory distress syndrome

,

renal insufficiency

,

capsule opacification

,

vision disorders

,

brachial plexus block

,

,

,

,

,

premature birth

,

,

macular degeneration

,

,

anesthesia and analgesia

,

migraine disorders

,

knee osteoarthritis

,

allergic conjunctivitis

,

cataract extraction

,

,

,

retinal detachment

,

sensorineural hearing loss

,

acute lung injury

,

posterior uveitis

,

,

,

,

anterior cruciate ligament injuries

,

shoulder injuries

,

,

,

,

,

anterior uveitis

,

,

postoperative complications

,

,

,

,

drug-related side effects and adverse reactions

,

,

residual neoplasm

,

,

,

pain management

,

,

spinal anesthesia

,

respiratory insufficiency

,

intravenous substance abuse

,

patient preference

,

intervertebral disc displacement

,

,

pathologic constriction

,

spinal stenosis

,

,

dissociative disorders

,

,

head and neck neoplasms

,

,

obstructive sleep apnea

,

peripheral arterial disease

,

peripheral vascular diseases

,

trigger finger disorder

,

intermediate uveitis

,

,

type 2 diabetes mellitus

,

carpal tunnel syndrome

,

,

wounds and injuries

,

gastrointestinal neoplasms

,

chronic kidney failure

,

,

colorectal neoplasms

,

,

hip osteoarthritis

,

anterior cruciate ligament reconstruction

,

shoulder impingement syndrome

,

graft vs host disease

,

,

penetrating keratoplasty

,

,

vitreoretinal surgery

,

,

,

,

refractive surgical procedures

,

,

femoral fractures

,

,

endophthalmitis

,

subdural hematoma

,

,

subdural hematoma chronic

,

postoperative cognitive complications

,

cognitive dysfunction

,

,

,

descemet stripping endothelial keratoplasty

,

femoral neck fractures

,

,

,

,

,

,

radius fractures

,

wrist fractures

,

,

,

,

spinal diseases

,

,

opioid-related disorders

,

urethral stricture

,

gastrointestinal diseases

,

inflammatory bowel diseases

,

digestive system diseases

,

intestinal diseases

,

ambulatory surgical procedures

,

nasal surgical procedures

,

general anesthesia

,

ankle fractures

,

,

pharmacokinetics

,

meibomian gland dysfunction

,

treatment outcome

,

,

,

corneal transplantation

,

intraocular pressure

,

vitamin d deficiency

,

,

hypoparathyroidism

,

viral bronchiolitis

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

systemic inflammatory response syndrome

,

,

orthopedic procedures

,

sleep apnea syndromes

,

corneal endothelial cell loss

,

,

,

,

,

status asthmaticus

,

meningeal tuberculosis

,

,

dental deposits

,

,

,

,

sjogren's syndrome

,

,

patient-controlled analgesia

,

,

chronic renal insufficiency

,

,

diabetic angiopathies

,

,

foot deformities

,

congenital foot deformities

,

walker-warburg syndrome

,

,

,

dupuytren contracture

,

,

fracture fixation

,

elbow tendinopathy

,

peripheral nervous system diseases

,

deglutition disorders

,

respiratory sounds

,

,

,

,

,

thyroid diseases

,

vascular diseases

,

,

digestive system neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

peritoneal neoplasms

,

cystadenocarcinoma

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

trophoblastic neoplasms

,

ventilator-associated pneumonia

,

abnormal karyotype

,

post-dural puncture headache

,

ureterolithiasis

,

rheumatoid arthritis

,

nerve compression syndromes

,

hypertrophic cicatrix

,

,

,

,

,

,

patient reported outcome measures

,

patient satisfaction

,

,

intractable pain

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

ocular hypertension

,

optic nerve diseases

,

cognition disorders

,

,

postherpetic neuralgia

,

,

hyaline membrane disease

,

,

,

,

trigeminal neuralgia

,

dentin sensitivity

,

,

,

,

,

,

thoracic surgical procedures

,

,

,

,

,

,

transient tachypnea of the newborn

,

,

,

thyroid neoplasms

,

vocal cord paralysis

,

female genital diseases

,

glucose intolerance

,

postoperative hemorrhage

,

surgical blood loss

,

,

perioperative period

,

parathyroid diseases

,

,

male breast neoplasms

,

,

biological availability

,

pruritus vulvae

,

meniere disease

,

vestibular diseases

,

intranasal administration

,

meconium aspiration syndrome

,

,

dental pulp necrosis

,

therapeutic equivalency

,

knee prosthesis

,

,

,

oxidative stress

,

antibiotic prophylaxis

,

intravenous administration

,

urinary retention

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

,

immunologic deficiency syndromes

,

common variable immunodeficiency

,

,

,

rheumatoid arthritis

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

frontotemporal dementia

,

primary progressive aphasia

,

pick disease of the brain

ventilator-associated pneumonia

,

breast neoplasms

,

triple negative breast neoplasms

,

,

non-small-cell lung carcinoma

,

renal cell carcinoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

,

breast neoplasms

,

triple negative breast neoplasms

,

,

,

hematologic neoplasms

,

myelodysplastic-myeloproliferative diseases

,

appendiceal neoplasms

,

,

pleural effusion

,

pleural neoplasms

,

castration-resistant prostatic neoplasms

,

primary myelofibrosis

,

myelomonocytic leukemia chronic

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelomonocytic leukemia juvenile

,

,

breast carcinoma in situ

,

cutaneous malignant melanoma

,

deltaretrovirus infections

,

htlv-i infections

,

,

composite lymphoma

,

hematologic diseases

,

,

heart disease risk factors

,

rectal neoplasms

,

abdominal neoplasms

,

sezary syndrome

,

urogenital neoplasms

,

ovarian diseases

,

,

gastrointestinal stromal tumors

,

squamous cell carcinoma of head and neck

,

esophageal squamous cell carcinoma

,

malignant pleural effusion

,

stomach neoplasms

,

male breast neoplasms

,

invasive hydatidiform mole

,

non-small-cell lung carcinoma

,

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

adult t-cell leukemia-lymphoma

,

aids-related lymphoma

,

urologic neoplasms

,

myelodysplastic syndromes

,

thyroid neoplasms

,

,

reactive arthritis

,

intestinal neoplasms

,

cholangiocarcinoma

,

cystadenocarcinoma

,

primary effusion lymphoma

,

thyroid diseases

,

t-cell lymphoma cutaneous

,

gastrointestinal neoplasms

,

myeloproliferative disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

biphenotypic leukemia acute

,

desmoplastic small round cell tumor

,

takotsubo cardiomyopathy

,

uterine neoplasms

,

,

myeloid leukemia chronic-phase

,

plasma cell leukemia

,

ductal carcinoma

,

neuroendocrine tumors

,

squamous cell carcinoma

,

germ cell and embryonal neoplasms

,

esophageal neoplasms

,

castleman disease

,

salivary gland neoplasms

,

anaplastic thyroid carcinoma

,

,

,

pathologic complete response

,

intestinal diseases

,

lymphomatoid granulomatosis

,

,

mycosis fungoides

,

,

,

colonic neoplasms

,

basal cell carcinoma

,

basal cell neoplasms

,

,

pancreatic ductal carcinoma

,

myeloid leukemia accelerated phase

,

residual neoplasm

,

adenoid cystic carcinoma

,

endocrine gland neoplasms

,

,

thymus neoplasms

,

febrile neutropenia

,

neoplasms by site

,

neurotoxicity syndromes

,

,

neoplasms by histologic type

,

hairy cell leukemia

,

intraocular lymphoma

,

hiv seropositivity

,

phenylketonurias

,

nervous system neoplasms

,

gallbladder neoplasms

,

diffuse intrinsic pontine glioma

,

neuroepithelial neoplasms

,

digestive system neoplasms

,

glandular and epithelial neoplasms

,

adjuvant chemotherapy

,

islet cell adenoma

,

,

,

immunoglobulin light-chain amyloidosis

,

,

patient participation

,

renal insufficiency

,

cortical blindness

,

blastic plasmacytoid dendritic cell neoplasm

,

antineoplastic combined chemotherapy protocols

,

paranasal sinus neoplasms

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

thromboembolism

,

thrombocytopenia

,

,

medullary carcinoma

,

,

small cell carcinoma

,

gene rearrangement

,

prolymphocytic leukemia t-cell

,

,

feasibility studies

,

vitamin d deficiency

,

,

,

prosthesis failure

,

,

,

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

lymphatic diseases

,

,

,

myxoid liposarcoma

,

histiocytic sarcoma

,

,

lymphangiosarcoma

,

experimental neoplasms

,

fibrous tissue neoplasms

,

optic nerve glioma

,

oligodendroglioma

,

disease progression

,

meningeal carcinomatosis

,

papillary adenocarcinoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

bile duct neoplasms

,

,

,

zollinger-ellison syndrome

,

adenoviridae infections

,

mouth neoplasms

,

,

extranodal extension

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

cardiac arrhythmias

,

,

endometrial stromal sarcoma

,

minimally invasive surgical procedures

,

neuroendocrine carcinoma

,

cystic fibrosis

,

,

,

fallopian tube neoplasms

,

,

,

,

endometrial neoplasms

,

neoplasm metastasis

,

peritoneal neoplasms

,

,

,

,

transitional cell carcinoma

,

,

kidney neoplasms

,

prostatic neoplasms

,

,

,

,

,

pancreatic neoplasms

,

small cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

colorectal neoplasms

,

,

hypersensitivity

,

,

t-cell leukemia

,

uterine cervical neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

myeloid leukemia acute

,

myeloid leukemia

,

clear cell adenocarcinoma

,

philadelphia chromosome

,

inflammatory breast neoplasms

,

malignant fibrous histiocytoma

,

,

malignant mesothelioma

,

primitive neuroectodermal tumors

,

renal cell carcinoma

,

,

,

cardiomyopathies

,

drug-related side effects and adverse reactions

,

mucinous cystadenocarcinoma

,

acinar cell carcinoma

,

neuroectodermal tumors

,

hemangiosarcoma

,

neurofibrosarcoma

,

adrenocortical carcinoma

,

brain neoplasms

,

ureteral neoplasms

,

primitive neuroectodermal tumors peripheral

,

synovial sarcoma

,

nerve sheath neoplasms

,

head and neck neoplasms

,

b-cell lymphoma marginal zone

,

urethral neoplasms

,

hand-foot syndrome

,

ganglioneuroblastoma

,

,

chemotherapy-induced febrile neutropenia

,

neoadjuvant therapy

,

,

waldenstrom macroglobulinemia

,

extranodal nk-t-cell lymphoma

,

,

central nervous system neoplasms

,

,

mullerian mixed tumor

,

benign fibrous histiocytoma

,

,

,

embryonal rhabdomyosarcoma

,

epstein-barr virus infections

,

female genital neoplasms

,

mucinous adenocarcinoma

,

,

,

peripheral nervous system diseases

,

,

therapeutic chemoembolization

,

,

,

clear cell sarcoma

,

alveolar rhabdomyosarcoma

,

,

,

connective and soft tissue neoplasms

,

,

ductal carcinoma breast

,

b-cell leukemia

,

adenomyoepithelioma

,

pulmonary blastoma

,

solitary fibrous tumors

,

hemangiopericytoma

,

pheochromocytoma

,

cognitive dysfunction

,

,

,

second primary neoplasms

,

soft tissue neoplasms

,

bone marrow diseases

,

alveolar soft part sarcoma

,

breast diseases

,

brain stem neoplasms

,

,

adenosquamous carcinoma

,

hereditary breast and ovarian cancer syndrome

,

pelvic neoplasms

,

dermatofibrosarcoma

,

adrenal cortex neoplasms

,

human herpesvirus 4

,

bone marrow transplantation

,

circulating neoplastic cells

,

perivascular epithelioid cell neoplasms

,

mesenchymal chondrosarcoma

,

,

granular cell tumor

,

genetic predisposition to disease

,

disease susceptibility

,

choroid plexus neoplasms

,

retinal neoplasms

,

lymphadenopathy

,

progression-free survival

,

beckwith-wiedemann syndrome

,

unknown primary neoplasms

,

medulloblastoma

,

connective tissue neoplasms

,

chemotherapy-related cognitive impairment

,

adjuvant radiotherapy

,

hyperthermic intraperitoneal chemotherapy

,

cytoreduction surgical procedures

,

hematopoietic stem cell mobilization

,

,

positron-emission tomography

,

adolescent development

,

,

breast neoplasms

,

,

large b-cell lymphoma diffuse

,

ovarian neoplasms

,

b-cell lymphoma

,

,

non-hodgkin lymphoma

,

,

ovarian epithelial carcinoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

hodgkin disease

,

liver neoplasms

,

lymphoid leukemia

,

hepatocellular carcinoma

,

multiple myeloma

,

triple negative breast neoplasms

,

plasma cell neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

follicular lymphoma

,

mantle-cell lymphoma

,

urinary bladder neoplasms

,

burkitt lymphoma

,

rhabdomyosarcoma

,

,

large-cell lymphoma anaplastic

,

,

,

immunoblastic lymphadenopathy

,

hemophagocytic lymphohistiocytosis

,

lymphoproliferative disorders

,

,

enteropathy-associated t-cell lymphoma

,

hematologic neoplasms

,

,

,

,

healthy volunteers/patients

,

human herpesvirus 8

,

retroperitoneal neoplasms

,

,

,

mediastinal neoplasms

,

non-muscle invasive bladder neoplasms

,

,

acquired immunodeficiency syndrome

,

cardiovascular diseases

,

pseudomyxoma peritonei

,

,

taste disorders

,

,

,

,

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

,

,

gonadal disorders

,

,

cerebrovascular disorders

,

therapeutic equivalency

,

,

pituitary neoplasms

,

sex cord-gonadal stromal tumors

,

,

sertoli-leydig cell tumor

,

,

,

pituitary diseases

,

leydig cell tumor

,

focal nodular hyperplasia

,

,

myocardial infarction

,

endomyocardial fibrosis

,

autonomic nervous system diseases

,

nervous system diseases

,

primary dysautonomias

,

,

liver transplantation

,

,

carcinoid tumor

,

malignant carcinoid syndrome

,

carcinoma in situ

,

eye abnormalities

,

tumor microenvironment

,

mitochondrial diseases

,

,

portal hypertension

,

,

alopecia areata

,

P2y purinoceptor 12

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